LLM-integrated applications are vulnerable to prompt injection attacks, where an attacker contaminates the input to inject malicious prompts, causing the LLM to follow the attacker's intent instead of the original user's. Existing prompt injection detection methods often have sub-optimal performance and/or high computational overhead. In this work, we propose PIShield, a detection method that is both effective and efficient. Our key observation is that the internal representation of the final token in a prompt-extracted from a specific layer of the LLM, which we term the injection-critical layer-captures distinguishing features between clean and contaminated prompts. Leveraging this insight, we train a simple linear classifier on these internal representations using a labeled set of clean and contaminated prompts. We compare PIShield against 11 baselines across 5 diverse benchmark datasets and 8 prompt injection attacks. The results demonstrate that PIShield is both highly effective and efficient, substantially outperforming existing methods. Additionally, we show that PIShield resists strong adaptive attacks.